Nike Air Zoom Structure 22. Women's Running Shoe. LIGHTWEIGHT SUPPORT. SLEEK DESIGN. The Nike Air Zoom Structure 22 Women's Running Shoe looks fast and feels secure. Engineered mesh, a heel overlay and dynamic support throughout the midfoot all work together to provide a smooth, stable ride. Flywire cables secure the top of your foot. Engineered mesh provides targeted ventilation and support. Dynamic Support provides a smooth, stable transition. Partial bootie wraps the foot for a snug, comfortable fit. Notches at the tongue provide easy on and off. Zoom Air unit in the forefoot delivers responsive, low-profile cushioning. Duralon blown rubber in the forefoot enhances cushioning.